Finbarr O’Sullivan


 

北京工商大学理学院数学系客座教授 ;


爱尔兰国立科克大学数学学院教授、院长、博士生导师。


通讯地址:北京市海淀区阜成路33 号理学院数学系,邮编:100048
Statistics Department, School of Mathematical Sciences, Western Gateway Building, University College Cork, Cork,
Ireland


电子信箱:f.osullivan@ucc.ie
电话:010-68985292
Degrees:


1979 B.Sc. Mathematical Science, University College Cork, Ireland.
1983 Ph.D. Statistics, University of Wisconsin, Madison, WI. USA.
Employment History:
1979‐1981: Statistical Consultant, Statistical Laboratory,UW,Madison,Wisconsin.
1981‐1982: Research Assistant, Statistics Department, UW,Madison,Wisconsin.
1984‐1987: Assistant Professor, Statistics Department, UC, Berkeley, California.
1988‐1989: Associate Professor, Statistics Department, UC, Berkeley, California.
1987‐1994: Associate Professor, Biostatistics and Statistics, UW, Seattle, Washington.
1994‐1998: Professor, Biostatistics and Statistics Departments, UW, Seattle, Washington.
1996‐Present: Professor and Chair of Statistics, University College Cork, Cork, Ireland.
1998‐Present: Affiliate Professor, Department of Radiology, UW, Seattle, Washington.
2011‐2013: Affiliate Professor, Department of Biostatistics, UW, Madison, Wisconsin.
2013‐Present, Head of School of Mathematical Sciences, University College Cork, Cork, Ireland.
2017‐2020: Adjunct professor of School of Science, Beijing Technology and Business
University.
Dr O’Sullivan (http://publish.ucc.ie/researchprofiles/D019/fosullivan) has over 30 years
academic research experience with over 75 peer-reviewed publications (excluding abstracts,
conference records and book chapters). He has served as associate editor of the SIAM Journal on
Scientific and Statistical Computing, the Journal of the American Statistical Association and
Biostatistics. He has had continuous research funding from NSF, NIH and HRB and SFI
throughout his academic career. He maintains strong collaborative links with a number of Positron
Emission Tomography imaging groups in the United States including: the University of Alabama,
the University of Pennsylvania, the University of Washington and the University of Wisconsin. He
supervises a number of PhD students and has provides on-going Biostatistical support to a range of
researchers in the US and Ireland.
Publications
Huang W, Chen Y, Fedorov A, Li X, Jajamovich GH,Malyarenko DI, Aryal MP, LaViolette PS,
Oborski MJ, O'Sullivan F, Abramson RG Jafari‐Khouzani K, Afzal A, Tudorica A, Moloney B,
Gupta SN,Besa C,Kalpathy‐Cramer J, Mountz JM,Laymon CM, Muzi M,Schmainda K, Cao
Y,Chenevert TL, Taouli B, Yankeelov TE, Fennessy F, and Li X, (2016). The Impact of Arterial
Input Function Determination Variations on Prostate Dynamic Contrast‐Enhanced Magnetic
Resonance Imaging Pharmacokinetic Modeling: A Multicenter Data Analysis Challenge.
Tomography: a journal for imaging research, 2(1), p.56‐66.
Ryan P., Furlong H.,Murphy C.G., O'Sullivan F., Walsh T.N., Shanahan F., and O'Sullivan GC.
(2015). "Prognostic significance of prospectively detected bone marrow micrometastases in
esophagogastric cancer: 10‐year follow‐up confirms prognostic significance." Cancer Medicine,
pp1281‐ 1288
Wangerin, K.A., Muzi, M., Peterson, L.M., Linden, H.M., Novakova, A., O'Sullivan, F., Kurland, B.F.,
Mankoff, D.A. and Kinahan, P.E., (2015). Effect of 18F‐FDG uptake time on lesion detectability
in PET imaging of early stage breast cancer. Tomography. Sep; 1(1): 53–60.
O’Sullivan F & Huang J (2014). An Analysis of Whole Body Tracer Kinetics in Dynamic PET
Studies with Application to Image‐Based Blood Input Function Extraction. IEEE Transactions
on Medical Imaging, VOL. 33, NO. 5, 1093‐1108.
Deo A, Borson S., Link, J., Domino,K., Eary, J., Ke,B., Richards,T, Mankoff, D.,Minoshima S.,
O'Sullivan,F., Eyal S., Hsiao P.,Maravilla K.,and Unadkat, J.D. (2014). "Activity of P‐glycoprotein,
a β‐amyloid transporter at the blood–brain barrier, is compromised in patients with mild
Alzheimer disease." Journal of Nuclear Medicine 55.7: 1106‐1111.
O'Sullivan F, Muzi M, Mankoff DM, Alexander M. Spence, Eary JF and Krohn KA (2014).
Voxel‐Level Mapping of Tracer Kinetics in PET Studies:A Statistical Approach Emphasizing
Tissue Life‐Tables; The annals of applied statistics 8.2: 1065‐1094
Eary JF, Conrad EU, O’Sullivan J, Hawkins DS, Schuetze SM, O’Sullivan F (2014); Sarcoma Mid‐
Therapy [F‐18]Fluorodeoxyglucose Positron Emission Tomography (FDG PET) and Patient
Outcome. The Journal of Bone & Joint Surgery. Jan;96(2):152‐158.
Roy Choudhury K, O'Sullivan F, Kasman I and Plowman GD (2012). ‘A comparison of least
squares and conditional maximum likelihood estimators under volume endpoint censoring in
tumor growth experiments’, Stat Med. 2012 Dec 20;31(29):4061‐73. doi: 10.1002/sim.5507.
Muzi, M., O'Sullivan, F., Mankoff, D. A., Doot, R. K., Pierce, L. A., Kurland, B. F., Linden,HM &
Kinahan, P. E. (2012). Quantitative assessment of dynamic PET imaging data in cancer
imaging. Magn Reson Imaging. 2012 Nov;30(9):1203‐15. doi: 10.1016/j.mri.2012.05.008.
Epub 2012 Jul 21
Huang J, O'Sullivan F and Jike L (2012). ‘Plane‐wave Sf S reconstruction of water surface
characteristics from Lambertian reflectance data’, Inverse Problems 28 065009
doi:10.1088/0266‐5611/28/6/065009
Hawe, D., Hernández Fernández, F. R., O'Suilleabháin, L., Huang, J., Wolsztynski, E., &
O'Sullivan, F. (2012). Kinetic analysis of dynamic positron emission tomography data using
open‐source image processing and statistical inference tools. Wiley Interdisciplinary Reviews:
Computational Statistics, 4(3), 316‐322.
O’Sullivan F, Wolsztynski E, O’Sullivan J, Richards T, Conrad EU, Eary JF. (2011). A Statistical
Modeling Approach to the Analysis of Spatial Patterns of FDG-PET Uptake in Human Sarcoma.
IEEE Transactions on Medical Imaging ;30(12):2059-2071.
O’Sullivan F, Kirrane J, Muzi M, O'Sullivan JN, Spence AM, Mankoff DA, Krohn KA (2010)
'Kinetic quantitation of cerebral PET‐FDG studies without concurrent blood sampling:
statistical recovery of the arterial input function'. IEEE Transactions in Medical Imaging, :610‐
624.
Roy Choudhury, K., O'Sullivan, F., Samanta, M., Caulliez, G., Shrira, V. (2010) 'Reconstruction of
wave height and slope fields from refracted images of water'. J.American Statist.Assoc,
(105):36‐47.
Chung FS, Eyal S, Muzi M, Link JM, Mankoff DA, Kaddoumi A, O'Sullivan F, Hsiao P, Unadkat JD
(2010). 'Positron emission tomography imaging of tissue P‐glycoprotein activity during
pregnancy in the non‐human primate'. British Journal of Pharmacology, :394‐404.
Eyal S, Chung FS, Muzi M, Link JM, Mankoff DA, Kaddoumi A, O'Sullivan F, Hebert MF, Unadkat
JD (2009). 'Simultaneous PET imaging of P‐glycoprotein inhibition in multiple tissues in the
pregnant nonhuman primate'. Journal of Nuclear Medicine, :798‐806.
O’Sullivan F, Muzi M, Spence AM, Mankoff DA, O'Sullivan JN, Fitzgerald N, Newman GC, Krohn
KA (2009). 'Nonparametric residue analysis of dynamic PET data with application to cerebral
FDG studies in normals'. Journal of the American Statistical Association, :556‐571.
Spence AM, Muzi M, Link JM, O'Sullivan F, Eary JF, Hoffman JM, Shankar LK, Krohn KA (2009)
'NCI‐Sponsored trial for the evaluation of safety and preliminary efficacy of 3'‐deoxy‐3'‐
[(18)F]fluorothymidine (FLT) as a marker of proliferation in patients with recurrent gliomas:
Preliminary efficacy studies'. Molecular Imaging and Biology, :343‐355.
O’Sullivan F, Huang J, Roy Choudhury K , Caulliez G and Shrira V (2008) 'Regularized
reconstruction of water surfaces from noisy gradient information via plane‐wave
superposition'. Inverse Problems, 24 (3) (034016)
Spence AM, Muzi M, Swanson KR, O'Sullivan F, Rockhill JK, Rajendran JG, Adamsen TC, Link JM,
Swanson PE, Yagle KJ, Rostomily RC, Silbergeld DL, Krohn KA (2008) 'Regional hypoxia in
glioblastoma multiforme quantified with [18F] Fluoromisonidazole positron emission
tomography before radiotherapy: correlation with time to progression and survival'. Clinical
Cancer Research, 14 (9):2623‐2630.
Eary J, O'Sullivan F, O'Sullivan J, Conrad E (2008) 'Spatial Heterogeneity in Sarcoma 18F‐FDG
Uptake as a Predictor of Patient Outcome'. The Journal of Nuclear Medicine, 49 (12):1973‐
1979.
Krohn KA, O'Sullivan F, Crowley J, Eary JF, Linden HM, Link JM, Mankoff DA, Muzi M, Joseph G.
Rajendran, Alexander M. Spence, Kristin R. Swanson. (2007). Challenges in Clinical Studies
with Multiple Imaging Probes. Nucl Med Biol. 2007 October; 34(7): 879–885
Mankoff DA, O'Sullivan F, Barlow WE, Krohn KA (2007) 'Molecular imaging research in the
outcomes era: measuring outcomes for individualized cancer therapy'. Academic Radiology,
14 (4):398‐405.
O'Sullivan, F and Roy Choudhury K (2006) 'A statistical measure of regularity for the study of
wind‐generated wave field images'. J. Amer. Statist. Assoc, 101 (475):1119‐1131.
Newman GC, Hospod FE, Patlak CS, Fain SE, Pulfer KA, Cook TD, O'Sullivan F (2006)
'Experimental estimates of the constants relating signal change to contrast concentration for
cerebral blood volume by T2* MRI'. Journal of Cerebral Blood Flow & Metabolism, 26 (6):760‐
770.
Muzi M, Spence AM, O'Sullivan F, Mankoff DA, Wells JM, Grierson JR,Link JM, Krohn KA (2006)
'Kinetic analysis of 3'‐deoxy‐3'‐18F‐fluorothymidine in patients with gliomas'. The Journal of
Nuclear Medicine, 47 (10):1612‐1621.
O’Sullivan F (2006) 'Locally constrained mixture representation of dynamic imaging data
from PET and MR studies'. Biostatistics, 7 (2):318‐338.
O’Sullivan F., Roy S., O'Sullivan J., Vernon C., and Eary JF. (2005) 'Incorporation of tumor shape
into an assessment of spatial heterogeneity for human sarcomas imaged with FDG‐PET'.
Biostatistics, 6 (2):293‐301.
Byrtek, M., O'Sullivan, F., Muzi, M., Spence, A.M. (2005) 'An adaptation of ridge regression for
improved estimation of kinetic model parameters from PET studies'.Nuclear Science,IEEE
Transactions, 52 (1):63‐68
Spence AM, Muzi M, Mankoff DA, O'Sullivan F, Link JM, Lewellen TK, Lewellen B, Pham P,
Minoshima S, Swanson K, Krohn KA (2004) '18F‐FDG PET of gliomas at delayed intervals:
improved distinction between tumor and normal gray matter'. The Journal of Nuclear
Medicine, 45 (10):1653‐1659.
Muzi M, Farwell DG, Krohn KA. (2004) 'Hypoxia and glucose metabolism in malignant tumors:
evaluation by [18F]fluoromisonidazole and [18F]fluorodeoxyglucose positron emission
tomography imaging'. Clinical Cancer Research, 10 (7):2245‐2252.
O’Sullivan F, Roy S, Eary J.: (2003) 'A statistical measure of tissue heterogeneity with
application to 3D PET sarcoma data'. Biostatistics, 4 (3):433‐448.
Muzi, M, Spence, AM, O'Sullivan, F, Mankoff, DA, Minoshima, S, Lewellen, B, Krohn, KA (2003)
'Delayed FDG imaging enhances relative tumor to brain uptake due to k4 difference'. The
Journal of Nuclear Medicine, 44 :241‐242.
Mulchrone, K. F., O'Sullivan, F. & Meere, P. A. (2003) 'Finite strain estimation using the mean
radial length of elliptical objects with bootstrap confidence intervals'. Journal of Structural
Geology, 25 (4):529‐538.
O’Sullivan F, O'Sullivan J, Bull AM, McGregor AH. (2003) 'Modelling multivariate
biomechanical measurements of the spine during a rowing exercise'. Clinical Biomechanics,
18 (6):488‐493.
Spence AM, Muzi M, Graham MM, O'Sullivan, F, Link J (2002) '2‐[18F] Fluoro‐2‐deoxyglucose
and Glucose Uptake in Malignant Gliomas Before and After Radiotherapy: Correlation with
Outcome'. Clinical Cancer Research, 8 :971‐979.
Graham MM, Muzi M, Spence AM, O'Sullivan F (2002) 'Fluorodeoxyglucose Lumped Constant
in Normal Brain'. The Journal of Nuclear Medicine, 43 :1157‐1166.
Wells JM, Mankoff DA, O'Sullivan F ,Eary JF (2002) 'Kinetic Analysis of 2‐[ ]‐Thymidine PET
Imaging Studies of Malignant Brain Tumors: Preliminary Patient Results'. Molecular Imaging,
1 (3):151‐159.
Eary JF, O'Sullivan F, Vernon C, Bruckner JD (2002) 'Sarcoma Tumor FDG Uptake Measured by
PET and Patient Outcome: A Retrospective Analysis'. European Journal of Nuclear Medicine,
29 (9):1149‐1154.
O'Sullivan, F and Roy Choudhury, K. (2001) 'An analysis of the role of positivity and mixture
model constraints in Poisson deconvolution problems'. J. Comput. Graph. Statist, 10 (4):673‐
696.
Eary JF, Mankoff DA, Spence AM, Berger MS, Olshen A, Link JM, O'Sullivan F, Krohn KA. (1999)
'2‐[C‐11]Thymidine Imaging of Malignant Brain Tumors'. Cancer Research, 59 (3):615‐621.
O’Sullivan F, Saha A (1999) 'Use of Ridge Regression for Improved Estimation of Kinetic
Constants from PET Data'. The IEEE Transactions on Medical Imaging, 18 (2):115‐125.
Maitra, R and O'Sullivan, F (1998) 'Variability assessment in positron emission tomography
and related generalized deconvolution models'. J. Amer. Statist. Assoc, 93 (444):1340‐1355.
Spence AM, Muzi M, Graham MM, O'Sullivan F, Krohn KA, Link JM, Lewellen TK, Lewellen B,
Freeman SD, Berger MS, Ojemann GA (1998) 'Glucose Metabolism in Human Malignant
Gliomas Measured Quantitatively with PET, 1‐[C‐11] Glucose and FDG: Analysis of the FDG
Lumped Constant'. The Journal of Nuclear Medicine, 39 (3):440‐448.
Bose, S.; O'Sullivan, F. (1997) 'A Region Based Image Segmentation Method for Multi‐Channel
Data [B1362]'. Journal of the American Statistical Association, 437 :92‐106.
Spence, A. M.; Graham, M. M.; Muzi, M.; Freeman, S. D.; Link, J. M.; Grierson, J. R.; O'Sullivan, F.;
Stein, D.; Abbott, G. L.; Krohn, K. A. (1997) 'Feasibility of Imaging Pentose Cycle Glucose
Metabolism in Gliomas With PET: Studies in Rat Brain Tumour Models [B1364]'. Journal of
Nuclear Medicine, 38 :617‐624.
Pawitan, Y.; Kohlmyer, S.; Lewellen, T.; O'Sullivan, F. (1997) 'PET Calibration and Attenuation
Correction'. IEEE Transactions on Nuclear Science, 44 :1249‐1253.
Olshen, A.; O'Sullivan, F. (1997) 'Camouflaged Deconvolution With Application to Blood Curve
Modeling in FDG PET Studies'. Journal of the American Statistical Association, 92 :1293‐1303.
Kooperberg, C. and O'Sullivan, F (1996) 'Predictive oscillation patterns: a synthesis of
methods for spatial‐temporal decomposition of random fields'. J. Amer. Statist. Assoc, 91
(436):1485‐1496.
O'Sullivan, F and Pawitan, Y. (1996) 'Bandwidth selection for indirect density estimation
based on corrupted histogram data'. J. Amer. Statist. Assoc, 91 (434):610‐626.
Cox, DD. and O'Sullivan, F (1996) 'Penalized likelihood‐type estimators for generalized
nonparametric regression'. J. Multivariate Anal, 56 (2):185‐206.
O’Sullivan F (1995) 'A study of least squares and maximum likelihood for image
reconstruction in positron emission tomography'. Ann. Statist, 23 (4):1267‐1300.
O’Sullivan F. (1994) 'Metabolic images from dynamic positron emission tomography studies'.
Statistical Methods in Medical Research, 3 :87‐101.
Cox DD and O'Sullivan F (1994) 'On the Sobolev Class of a Composite Function'. Proceedings
of The American Mathematical Society, Vol. 122, No. 3 (Nov., 1994), pp. 727‐732
O’Sullivan F and Qian M (1994) 'A Regularized Contrast Statistic for Object Boundary
Estimation‐Implementation and Statistical Evaluation'. IEEE Transactions on Pattern Analysis
and Machine Intelligence, 16 (6):561‐570.
O'Sullivan, F (1993) 'Nonparametric estimation in the Cox model'. Ann. Statist, 21 (1):124‐145.
O'Sullivan F, Pawitan Y (1993) 'Multidimensional density estimation by tomography'. Journal
of the Royal Statistical Society, Series B, Vol. 55, No. 2 (1993), pp. 509‐521
O’Sullivan F (1993) 'Mixture estimation with multichannel image data'. Journal of The
American Statistical Association, Vol. 88, No. 421 (Mar., 1993), pp. 209‐220
Pawitan, Y and O'Sullivan, F. (1993) 'Data‐dependent bandwidth selection for emission
computed tomography reconstruction'. The IEEE Transactions on Medical Imaging, 12
(2):167‐172.
O’Sullivan F., Pawitan Y and Haynor D.R.: (1993) 'Reducing negative artifacts in emission
tomography reconstructions: post‐processing filtered backprojection solutions'. The IEEE
Transactions on Medical Imaging, 12 :653‐663.
O’Sullivan F (1993) 'Imaging radiotracer model parameters in PET: A mixture analysis
approach'. The IEEE Transactions on Medical Imaging, 12 :399‐412.
O'Sullivan, F (1991) 'Sensitivity analysis for regularized estimation in some system
identification problems'. SIAM J. Sci. Statist. Comput, 12 (6):1266‐1283.
O’Sullivan F (1991) 'Discussion: Multivariate Adaptive Regression Splines'. Annals of Statistics,
19 (1):99‐102.
O’Sullivan F (1991) 'Discretized Laplacian Smoothing by Fourier Methods'. Journal of The
American Statistical Association, Vol. 86, No. 415 (Sep., 1991), pp. 634‐642
O'Sullivan, F (1990) 'Convergence characteristics of methods of regularization estimators for
nonlinear operator equations'. SIAM J. Numer. Anal, 27 (6):1635‐1649.
Wash CH, Stewart M, O'Sullivan F, Motell CE (1990) 'Rain Estimation from Infrared and Visible
GOES Satellite Data'. Journal of Applied Meteorology, 29 (3):209‐223.
Cox, DD and O'Sullivan, F (1990) 'Asymptotic analysis of penalized likelihood and related
estimators'. Ann. Statist, 18 (4):1676‐1695.
O’Sullivan F (1990) 'An Iterative Approach to Two‐Dimensional Laplacian Smoothing with
Application Image Restoration'. Journal of The American Statistical Association, Vol. 85, No.
409 (Mar., 1990), pp. 213‐219
O'Sullivan, F (1988) 'Nonparametric estimation of relative risk using splines and crossvalidation'.
SIAM J. Sci. Statist. Comput, 9 (3):531‐542.
O’Sullivan F and O'Sullivan J (1988) 'Deconvolution of Episodic Hormone Data: An analysis of
the Role of Season on the Onset of Puberty in Cows'. Biometrics, Vol. 44, No. 2 (Jun., 1988), pp.
339‐353
O'Sullivan, F (1988) 'Fast computation of fully automated log‐density and log‐hazard
estimators'. SIAM J. Sci. Statist. Comput, 9 (2):363‐379.
O’Sullivan F (1987) 'Non‐Gaussian State‐Space Modeling of Nonstationary Time Series:
Comment'. Journal of The American Statistical Association, 82:1044‐1046
O'Sullivan,F ,Yandell BF and Raynor WJ (1986) 'Automatic Smoothing of Regression Functions
in Generalized Linear Models'. Journal of the American Statistical Association, 81 :96‐104.
O'Sullivan, F (1986) 'A statistical perspective on ill‐posed inverse problems'. Statist. Sci, 1
(4):502‐527.
O'Sullivan,F, Wahba G (1985) 'A cross validated Bayesian retrieval algorithm for non‐linear
remote sensing experiments'. Journal of Computational Physics, 59 :441‐455.
O’Sullivan F (1985) 'Discussion of some aspects of the spline smoothing approach to nonparametric
regression curve fitting'. Journal of the Royal Statistical Society, Series B, 47:54‐55.
O’Sullivan F, Whitney P, Hinshelwood MM and Hauser ER (1984) 'The Analysis of Repeated
Measures Experiments in Endocrinology'. Journal of Animal Science, 59:1070‐1079.
Presentations since 2012
Huang, J., Mou, T. O’Sullivan, F. Application of Gamma Statistics in the Analysis of Kinetic
Models for Dynamic PET Time Course Data; Journal of Nuclear Medicine 57, no. supplement 2
(2016): 154‐154.
Muzi, M., Fink, J., O'Sullivan, F., O'Sullivan, J.N., Kinahan, P. and Krohn, K., Assessment of
cellular proliferation in recurrent primary brain cancer with 3'‐deoxy‐3'‐18F‐fluorothymidine
PET imaging. Journal of Nuclear Medicine, 57(supplement 2),2016, pp.366‐366.
Peterson, L, Novakova A, O'Sullivan J, O'Sullivan F, Shields A, Montgomery S, Linden H et al.
"Use of paired FDG and 18F‐Fluoride PET to predict response to therapy in patients with bone
dominant metastases from breast cancer." Journal of Nuclear Medicine 57, no. supplement 2
(2016): 415‐415.
Hughes N, Mou T, O’Regan K, Murphy P, O’Sullivan J, Wolsztynski E, Huang J, Kennedy M, Eary
JF, O’Sullivan F.; Prognostic value of tumor heterogeneity evaluated by FDG‐PET/CT imaging
in lung cancer patients. J Clin Oncol 34, 2016 (suppl; abstr 11564) 2016 American Society of
Clinical Oncology Annual Meeting, Chicago, IL
Specht JM, Peterson L, Novakova A, O'Sullivan JN, O'Sullivan F, Shields A, Montgomery A,
Linden HM, Gralow J, Ellis GK,. Gadi VK,Barlow WE, Doot RK, Schubert EK, Dunnwald LK,
MacDonald L,Kinahan P, Mankoff DASerial FDG‐PET to predict response, time to skeletal
related events, and survival in patients with bone‐dominant metastatic breast cancer.. J Clin
Oncol 34, 2016 (suppl; abstr 11569); 2016 American Society of Clinical Oncology Annual
Meeting, Chicago, IL
T. Mou, J. Huang, Y. Zhang, P. Kinahan, F. O'Sullivan; An Improved Statistical Approach to the
Estimation of Spatial Bias and Variability in Reconstructed PET Data; 2015 Nuclear Science
Symposium and Medical Imaging Conference, San Diego,CA
J. Huang, T. Mou, M. Muzi, F. O'Sullivan; 3‐D Model‐Based Correction of Artifacts Generated by
Localized High‐Intensities in a PET Scanner; 2015 Nuclear Science Symposium and Medical
Imaging Conference, San Diego,CA
F. R. Hernandez Fernandez, F. O'Sullivan; Improved Poisson‐Guided Clustering of Dynamic
PET Imaging Data to Extract Shape Patterns for Mixture Modelling and Parametric Imaging;
2015 Nuclear Science Symposium and Medical Imaging Conference, San Diego,CA
E. Wolsztynski, J. O'Sullivan, M. P. Kennedy, K. O'Regan, J. F. Eary, F. O'Sullivan; Structural
Analysis of Solid Tumors Based on Regularized Tubular Modeling; 2015 Nuclear Science
Symposium and Medical Imaging Conference, San Diego,CA
O'Sullivan, F., Huang, J., Muzi, M. and Krohn, K., 2015. A Patlak‐guided approach to extracting
AIF information from regions with significant tracer retention. Journal of Nuclear Medicine,
56(supplement 3), pp.624‐624.
Peterson, L., O'Sullivan, J., O'Sullivan, F., Koh, W.J., Swensen, R., Krohn, K., Eary, J., Shankar, L.
and Rajendran, J., 2015. FMISO PET uptake and spatial heterogeneity to predict response in
patients with cervical cancer. Journal of Nuclear Medicine, 56(supplement 3), pp.1175‐1175.
O'Sullivan,F.,Muzi,M., O'Sullivan J., Wolszynski E., Fink J., Eary J., Krohn KA.;Prognostic value of
spatial heterogeneity in FMISO‐PET images of hypoxia in brain cancer patients.; J Nucl Med.
2014; 55 (Supplement 1):449
Finbarr O'Sullivan, Janet O'Sullivan, Lisa Dunnwald, Mark Muzi, Jian Huang, Erin Schubert,
Lanell Peterson, Robert Doot, David Mankoff; Automatic recovery of the arterial input
function for PET imaging studies with water and FDG in locally advanced breast cancer
patients. J Nucl Med. 2014; 55 (Supplement 1):430
Finbarr O'Sullivan, Janet O'Sullivan, Lisa Dunnwald, Mark Muzi, Jian Huang, Erin Schubert,
Lanell Peterson, Robert Doot, David Mankoff; Imaging tracer kinetics by mixtures of residues:
An investigation in the context of dynamic PET studies with 15O‐H2O (water) and 18F‐FDG
for locally advanced breast cancer; J Nucl Med. 2014; 55 (Supplement 1):431
Janet Eary, Janet O'Sullivan and Finbarr O'Sullivan ; Prognostic value of mid‐therapy FDG PET
heterogeneity in sarcoma patients, J Nucl Med. 2014; 55 (Supplement 1):226
Finbarr O’Sullivan ‐ Measurement of Cancer Heterogeneity with Positron Emission
Tomography (PET) Data; Presentation at Mathematical Biosciences Workshop March 2014
Columbus, OH
O'Sullivan F, Muzi M, Fink, J, Rockhill, J, Eary J, Krohn, K; Quantitative metabolic imaging of
kinetic parameters from dynamic PET [F‐18]‐Fluorothymidine (FLT) data with application to
studies in brain cancer patients; J NUCL MED MEETING ABSTRACTS 2013 54: 2039
Wolsztynski, E, O'Sullivan F, O'Sullivan J, Conrad, E, Eary J; Cluster‐based evaluation of change
in static FDG‐PET uptake information for therapeutic response quantitation; J NUCL MED
MEETING ABSTRACTS 2013 54: 2094
O'Sullivan F, Huang, J, Muzi M, O'Sullivan J, Fink J, Rockhill J, Eary JF, Krohn K; Validation of an
image derived blood time course extraction method for quantitation of dynamic PET [F‐18]‐
Fluorothymidine (FLT) studies in brain cancer patients; J NUCL MED MEETING ABSTRACTS
2013 54: 2040
Muzi M, Fink, J, Rockhill, J, O'Sullivan F, Wolsztynski E, Eary J, Krohn, K; Parametric image
analysis of FLT data shows spatial differences between transport and proliferation; J NUCL
MED MEETING ABSTRACTS 2013 54: 2135
Eary J, O'Sullivan J, O'Sullivan F, Conrad, E; Prognostic value of mid‐therapy FDG PET in
sarcoma patients; J NUCL MED MEETING ABSTRACTS 2013 54: 602
Muzi M, J O'Sullivan J Rockhill, J Fink, O'Sullivan F, Eary J, and Krohn K; Quantitative [F‐18]‐
fluoromisonidazole (FMISO) imaging of hypoxia in brain cancer patients; J. NUCL. Med.
MEETING ABSTRACTS, May 2013; 54: 1830.
A Multigrid Approach to ML Reconstruction in PET: A Fast Alternative to EM‐Based
Techniques; F. O'Sullivan and L. O'Suilleabhain; poster IEEE Nuclear Science Symposium and
Medical Imaging Conference, 2013, Seoul, Korea
F. O’Sullivan, J. Scheuermann, M. Muzi, A. Opanowski, P. E. Kinahan; A Statistical Analysis of
Sources of Systematic and Random Variation in Dynamically Imaged Uniform Cyclinder Data
from an ACRIN Study of PET Scanning Sites for Cancer Imaging Trials; poster IEEE Nuclear
Science Symposium and Medical Imaging Conference, 2013, Seoul, Korea
J. Huang, E. Wolsztynski, D. Hawe, K.‐M. Kim, K. Roy Choudhury, F. O’Sullivan; A Cautionary
Note on the Use of Constrained Reconstructions for Quantification of Regional PET Imaging
Data; poster IEEE Nuclear Science Symposium and Medical Imaging Conference, 2013, Seoul,
Korea
O'Sullivan F, Muzi M, Huang J, Eary JF, Link J, Krohn KA; A Fully Automatic Procedure for
Image Derived Blood Extraction, Including Assessment of Metabolite, in Dynamic PET
Fluorothymidine (FLT) Studies; European Journal of Cancer ‐ November 2012 (Vol.
48Supplement 6, Page 80, DOI: 10.1016/S0959‐8049(12)72059‐2)
Kwee S, Narayanan M, Watanabe A, O'Suilleabhain L, Wolsztynski E, Wong L and O'Sullivan F;
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